Mechanistic Biologist
Retro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to rejuvenate cell and tissue function with the ultimate aim of adding 10 years to healthy human lifespan.
We’re building a mission-driven team of accomplished and kind individuals who embrace our startup culture of rapid iteration, transparency, and versatility.
Our autophagy program is advancing rapidly and leading the charge in translating our science into a first-in-human clinical trial, marking a major step toward delivering transformative therapies rooted in the biology of aging.
We’re hiring a new team member to help us build and refine the tools we need to evaluate our next-generation autophagy-enhancing compounds. This role is at the heart of our discovery-to-clinic transition—translating biological insight into robust, reproducible assays that drive compound selection and development.
The role:
You’ll be responsible for designing, optimizing, and executing cell-based assays to measure compound activity, mechanism of action (MOA), and potency. Your work will ensure our assays are aligned with the program’s evolving needs from early discovery through IND and into the clinic. You’ll report to the autophagy program lead and will be highly cross-functional, working closely with our computational and translational biologists, as well as external CROs.
About you:
You share our sense of urgency and excitement, and thrive in fast-paced, interdisciplinary environments. You work well independently but will also enjoy being part of a highly-collaborative, multi-disciplinary team. You are excited to work on, and solve, hard problems and ultimately help extend healthy human lifespan!
In this role you will:
You will thrive in this role if you:
It’s a bonus if you:
Total compensation also includes generous equity and benefits including:
- Medical, dental, and vision insurance for you and your family
- 401(k) plan with 4% matching
- Flexible time off and 10 company holidays per year
- Paid parental leave
- Annual learning & development stipend
- Daily Retro-sponsored lunch and snacks
Additional Information
We take pride in cultivating an environment that fosters collaboration, open communication, and authenticity. We believe that great results are best delivered by a highly creative team working in concert. We are an equal opportunity employer; we do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We are diverse in background and singular in mission.
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